Novel Targeted Anti-Tumor Nanoparticles Developed from Folic Acid-Modified 2-Deoxyglucose

The glucose analog, 2-deoxyglucose (2-DG), specifically inhibits glycolysis of cancer cells and interferes with the growth of cancer cells. However, the excellent water solubility of 2-DG makes it difficult to be concentrated in tumor cells. In this study, a targeted nano-pharmacosome was developed...

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Detalles Bibliográficos
Autores principales: Jin, Shaoming, Du, Zhongyao, Guo, Huiyuan, Zhang, Hao, Ren, Fazheng, Wang, Pengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386969/
https://www.ncbi.nlm.nih.gov/pubmed/30736291
http://dx.doi.org/10.3390/ijms20030697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386969/
https://www.ncbi.nlm.nih.gov/pubmed/30736291
http://dx.doi.org/10.3390/ijms20030697

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