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Novel Targeted Anti-Tumor Nanoparticles Developed from Folic Acid-Modified 2-Deoxyglucose
The glucose analog, 2-deoxyglucose (2-DG), specifically inhibits glycolysis of cancer cells and interferes with the growth of cancer cells. However, the excellent water solubility of 2-DG makes it difficult to be concentrated in tumor cells. In this study, a targeted nano-pharmacosome was developed...
Autores principales: | Jin, Shaoming, Du, Zhongyao, Guo, Huiyuan, Zhang, Hao, Ren, Fazheng, Wang, Pengjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386969/ https://www.ncbi.nlm.nih.gov/pubmed/30736291 http://dx.doi.org/10.3390/ijms20030697 |
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