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mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in regulation of cell survival, metabolism, growth and protein synthesis in response to upstream signals in both normal physiological and pathological conditions, especially in cancer. Aberrant mTOR signaling result...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Li, Xiaoyi, Zhang, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387042/
https://www.ncbi.nlm.nih.gov/pubmed/30754640
http://dx.doi.org/10.3390/ijms20030755