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mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy
The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in regulation of cell survival, metabolism, growth and protein synthesis in response to upstream signals in both normal physiological and pathological conditions, especially in cancer. Aberrant mTOR signaling result...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387042/ https://www.ncbi.nlm.nih.gov/pubmed/30754640 http://dx.doi.org/10.3390/ijms20030755 |