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Cancer-Specifically Re-Spliced TSG101 mRNA Promotes Invasion and Metastasis of Nasopharyngeal Carcinoma

TSG101 (Tumor susceptibility 101) gene and its aberrantly spliced isoform, termed TSG101∆154-1054, are tightly linked to tumorigenesis in various cancers. The aberrant TSG101∆154-1054 mRNA is generated from cancer-specific re-splicing of mature TSG101 mRNA. The TSG101∆154-1054 protein protects the f...

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Detalles Bibliográficos
Autores principales: Chua, Huey-Huey, Kameyama, Toshiki, Mayeda, Akila, Yeh, Te-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387056/
https://www.ncbi.nlm.nih.gov/pubmed/30759747
http://dx.doi.org/10.3390/ijms20030773