Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration?

The retinal pigment epithelium (RPE) forms the outer blood–retina barrier and facilitates the transepithelial transport of glucose into the outer retina via GLUT1. Glucose is metabolized in photoreceptors via the tricarboxylic acid cycle (TCA) and oxidative phosphorylation (OXPHOS) but also by aerob...

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Detalles Bibliográficos
Autores principales: Léveillard, Thierry, Philp, Nancy J., Sennlaub, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387069/
https://www.ncbi.nlm.nih.gov/pubmed/30754662
http://dx.doi.org/10.3390/ijms20030762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387069/
https://www.ncbi.nlm.nih.gov/pubmed/30754662
http://dx.doi.org/10.3390/ijms20030762

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