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TRAF6 Silencing Attenuates Multiple Myeloma Cell Adhesion to Bone Marrow Stromal Cells

The bone marrow (BM) microenvironment plays an important role in supporting proliferation, survival and drug resistance of Multiple Myeloma (MM) cells. MM cells adhere to bone marrow stromal cells leading to the activation of tumour-promoting signaling pathways. Activation of the NFκB pathway, in pa...

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Detalles Bibliográficos
Autores principales: Morgan, Jonathan J., McAvera, Roisin M., Crawford, Lisa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387103/
https://www.ncbi.nlm.nih.gov/pubmed/30736330
http://dx.doi.org/10.3390/ijms20030702