Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy

Wilms tumor protein-1 (WT1) is an attractive target for adoptive T-cell therapy due to its expression in solid tumors and hematologic malignancies. However, T cells recognizing WT1 occur in low frequencies in the peripheral blood of healthy donors, limiting potential therapeutic possibilities. Tin m...

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Detalles Bibliográficos
Autores principales: Schillingmann, Damaris A., Riese, Sebastian B., Vijayan, Vijith, Tischer-Zimmermann, Sabine, Schmetzer, Helga, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Immenschuh, Stephan, Eiz-Vesper, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387130/
https://www.ncbi.nlm.nih.gov/pubmed/30678050
http://dx.doi.org/10.3390/ijms20030482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387130/
https://www.ncbi.nlm.nih.gov/pubmed/30678050
http://dx.doi.org/10.3390/ijms20030482

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