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Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy
Wilms tumor protein-1 (WT1) is an attractive target for adoptive T-cell therapy due to its expression in solid tumors and hematologic malignancies. However, T cells recognizing WT1 occur in low frequencies in the peripheral blood of healthy donors, limiting potential therapeutic possibilities. Tin m...
Autores principales: | Schillingmann, Damaris A., Riese, Sebastian B., Vijayan, Vijith, Tischer-Zimmermann, Sabine, Schmetzer, Helga, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Immenschuh, Stephan, Eiz-Vesper, Britta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387130/ https://www.ncbi.nlm.nih.gov/pubmed/30678050 http://dx.doi.org/10.3390/ijms20030482 |
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