Association of the MDM2 SNP285 and SNP309 Genetic Variants with the Risk, Age at Onset and Prognosis of Breast Cancer in Central European Women: A Hospital-Based Case-Control Study

SNP309T>G (rs2279744) and SNP285G>C (rs117039649) in the MDM2 promoter are thought to have opposite effects on the binding of transcription factor SP1 (specificity protein 1), and consequently on MDM2 expression, p53 levels, cancer risk, age at onset, and prognosis. Here, we genotyped SNP309 a...

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Detalles Bibliográficos
Autores principales: Miedl, Heidi, Lebhard, Jürgen, Ehart, Lisa, Schreiber, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387136/
https://www.ncbi.nlm.nih.gov/pubmed/30691044
http://dx.doi.org/10.3390/ijms20030509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387136/
https://www.ncbi.nlm.nih.gov/pubmed/30691044
http://dx.doi.org/10.3390/ijms20030509

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