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Interleukin-18 in Health and Disease

Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ product...

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Detalles Bibliográficos
Autores principales: Yasuda, Koubun, Nakanishi, Kenji, Tsutsui, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387150/
https://www.ncbi.nlm.nih.gov/pubmed/30717382
http://dx.doi.org/10.3390/ijms20030649