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Mechanisms of Developmental Toxicity of Dioxins and Related Compounds

Dioxins and related compounds induce morphological abnormalities in developing animals in an aryl hydrocarbon receptor (AhR)-dependent manner. Here we review the studies in which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is used as a prototypical compound to elucidate the pathogenesis of morphologi...

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Detalles Bibliográficos
Autores principales: Yoshioka, Wataru, Tohyama, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387164/
https://www.ncbi.nlm.nih.gov/pubmed/30708991
http://dx.doi.org/10.3390/ijms20030617