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BmK AEP, an Anti-Epileptic Peptide Distinctly Affects the Gating of Brain Subtypes of Voltage-Gated Sodium Channels

BmK AEP, a scorpion peptide purified form the venom of Buthus martensii Karsch, has been reported to display anti-epileptic activity. Voltage-gated sodium channels (VGSCs) are responsible for the rising phase of action potentials (APs) in neurons and, therefore, controlling neuronal excitability. To...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Wu, Ying, Zou, Xiaohan, Tang, Qinglian, Zhao, Fang, Cao, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387193/
https://www.ncbi.nlm.nih.gov/pubmed/30744067
http://dx.doi.org/10.3390/ijms20030729