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Negative Regulatory Loop between Microphthalmia-Associated Transcription Factor (MITF) and Notch Signaling
Melanoma, a melanocyte-origin neoplasm, is a highly metastatic and treatment-resistance cancer. While it is well established that notch signaling activation promotes melanoma progression, little is known about the reciprocal interactions between Notch signaling and melanoma-specific pathways. Here w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387231/ https://www.ncbi.nlm.nih.gov/pubmed/30699982 http://dx.doi.org/10.3390/ijms20030576 |