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Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells

Insulin-resistance is a characteristic feature of type 2 diabetes (T2D) and plays a major role in the pathogenesis of this disease. Skeletal muscles are quantitatively the biggest glucose users in response to insulin and are considered as main targets in development of insulin-resistance. It is now...

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Detalles Bibliográficos
Autores principales: Bandet, Cécile L., Tan-Chen, Sophie, Bourron, Olivier, Le Stunff, Hervé, Hajduch, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387241/
https://www.ncbi.nlm.nih.gov/pubmed/30678043
http://dx.doi.org/10.3390/ijms20030479