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Sphingolipid Metabolism: New Insight into Ceramide-Induced Lipotoxicity in Muscle Cells
Insulin-resistance is a characteristic feature of type 2 diabetes (T2D) and plays a major role in the pathogenesis of this disease. Skeletal muscles are quantitatively the biggest glucose users in response to insulin and are considered as main targets in development of insulin-resistance. It is now...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387241/ https://www.ncbi.nlm.nih.gov/pubmed/30678043 http://dx.doi.org/10.3390/ijms20030479 |