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Hypoxia Induced ER Stress Response as an Adaptive Mechanism in Cancer

It is evident that regions within tumors are deprived of oxygen, which makes the microenvironment hypoxic. Cancer cells experiencing hypoxia undergo metabolic alterations and cytoprotective adaptive mechanisms to survive such stringent conditions. While such mechanisms provide potential therapeutic...

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Detalles Bibliográficos
Autores principales: Chipurupalli, Sandhya, Kannan, Elango, Tergaonkar, Vinay, D’Andrea, Richard, Robinson, Nirmal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387291/
https://www.ncbi.nlm.nih.gov/pubmed/30754624
http://dx.doi.org/10.3390/ijms20030749