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Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism

An intriguing target involved in several pathophysiological processes is the 18 kDa translocator protein (TSPO), of which exact functions remained elusive until now. A single nucleotide polymorphism in the TSPO gene influences the binding affinity of endogenous and synthetic TSPO ligands by facilita...

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Detalles Bibliográficos
Autores principales: Berroterán-Infante, Neydher, Tadić, Monika, Hacker, Marcus, Wadsak, Wolfgang, Mitterhauser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387295/
https://www.ncbi.nlm.nih.gov/pubmed/30699908
http://dx.doi.org/10.3390/ijms20030563