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The Selective Acetamidine-Based iNOS Inhibitor CM544 Reduces Glioma Cell Proliferation by Enhancing PARP-1 Cleavage In Vitro

Gliomas are the most aggressive adult primary brain tumors. Expression of inducible Nitric Oxide Synthase has been reported as a hallmark of chemoresistance in gliomas and several studies have reported that inhibition of inducible Nitric Oxide Synthase could be related to a decreased proliferation o...

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Detalles Bibliográficos
Autores principales: Gallorini, Marialucia, Maccallini, Cristina, Ammazzalorso, Alessandra, Amoia, Pasquale, De Filippis, Barbara, Fantacuzzi, Marialuigia, Giampietro, Letizia, Cataldi, Amelia, Amoroso, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387310/
https://www.ncbi.nlm.nih.gov/pubmed/30678338
http://dx.doi.org/10.3390/ijms20030495