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The Selective Acetamidine-Based iNOS Inhibitor CM544 Reduces Glioma Cell Proliferation by Enhancing PARP-1 Cleavage In Vitro
Gliomas are the most aggressive adult primary brain tumors. Expression of inducible Nitric Oxide Synthase has been reported as a hallmark of chemoresistance in gliomas and several studies have reported that inhibition of inducible Nitric Oxide Synthase could be related to a decreased proliferation o...
Autores principales: | Gallorini, Marialucia, Maccallini, Cristina, Ammazzalorso, Alessandra, Amoia, Pasquale, De Filippis, Barbara, Fantacuzzi, Marialuigia, Giampietro, Letizia, Cataldi, Amelia, Amoroso, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387310/ https://www.ncbi.nlm.nih.gov/pubmed/30678338 http://dx.doi.org/10.3390/ijms20030495 |
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