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Accessibility of Cations to the Selectivity Filter of KcsA in the Inactivated State: An Equilibrium Binding Study

Cation binding under equilibrium conditions has been used as a tool to explore the accessibility of permeant and nonpermeant cations to the selectivity filter in three different inactivated models of the potassium channel KcsA. The results show that the stack of ion binding sites (S1 to S4) in the i...

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Detalles Bibliográficos
Autores principales: Giudici, Ana Marcela, Renart, Maria Lourdes, Díaz-García, Clara, Morales, Andrés, Poveda, José Antonio, González-Ros, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387330/
https://www.ncbi.nlm.nih.gov/pubmed/30764559
http://dx.doi.org/10.3390/ijms20030689