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Impact of Mechanical Load on the Expression Profile of Synovial Fibroblasts from Patients with and without Osteoarthritis

Osteoarthritis (OA) affects the integrity of the entire joint including the synovium. The most abundant cells in the synovium are fibroblasts (SF). Excessive mechanical loading might contribute to OA pathogenesis. Here, we investigate the effects of mechanical loading on SF derived from non-OA (N-SF...

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Detalles Bibliográficos
Autores principales: Schröder, Agnes, Nazet, Ute, Muschter, Dominique, Grässel, Susanne, Proff, Peter, Kirschneck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387339/
https://www.ncbi.nlm.nih.gov/pubmed/30704030
http://dx.doi.org/10.3390/ijms20030585