The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS

The 18 kDa Translocator Protein (TSPO) is a marker for microglial activation as its expression is enhanced in activated microglia during neuroinflammation. TSPO ligands can attenuate neuroinflammation and neurotoxicity. In the present study, we examined the efficacy of new TSPO ligands designed by o...

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Detalles Bibliográficos
Autores principales: Azrad, Maya, Zeineh, Nidal, Weizman, Abraham, Veenman, Leo, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387401/
https://www.ncbi.nlm.nih.gov/pubmed/30704062
http://dx.doi.org/10.3390/ijms20030594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387401/
https://www.ncbi.nlm.nih.gov/pubmed/30704062
http://dx.doi.org/10.3390/ijms20030594

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