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The TSPO Ligands 2-Cl-MGV-1, MGV-1, and PK11195 Differentially Suppress the Inflammatory Response of BV-2 Microglial Cell to LPS
The 18 kDa Translocator Protein (TSPO) is a marker for microglial activation as its expression is enhanced in activated microglia during neuroinflammation. TSPO ligands can attenuate neuroinflammation and neurotoxicity. In the present study, we examined the efficacy of new TSPO ligands designed by o...
Autores principales: | Azrad, Maya, Zeineh, Nidal, Weizman, Abraham, Veenman, Leo, Gavish, Moshe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387401/ https://www.ncbi.nlm.nih.gov/pubmed/30704062 http://dx.doi.org/10.3390/ijms20030594 |
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