Human ApoA-I Overexpression Enhances Macrophage-Specific Reverse Cholesterol Transport but Fails to Prevent Inherited Diabesity in Mice

Human apolipoprotein A-I (hApoA-I) overexpression improves high-density lipoprotein (HDL) function and the metabolic complications of obesity. We used a mouse model of diabesity, the db/db mouse, to examine the effects of hApoA-I on the two main functional properties of HDL, i.e., macrophage-specifi...

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Detalles Bibliográficos
Autores principales: Méndez-Lara, Karen Alejandra, Farré, Núria, Santos, David, Rivas-Urbina, Andrea, Metso, Jari, Sánchez-Quesada, José Luis, Llorente-Cortes, Vicenta, Errico, Teresa L., Lerma, Enrique, Jauhiainen, Matti, Martín-Campos, Jesús M., Alonso, Núria, Escolà-Gil, Joan Carles, Blanco-Vaca, Francisco, Julve, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387412/
https://www.ncbi.nlm.nih.gov/pubmed/30717414
http://dx.doi.org/10.3390/ijms20030655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387412/
https://www.ncbi.nlm.nih.gov/pubmed/30717414
http://dx.doi.org/10.3390/ijms20030655

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