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Gold Nanoparticle-Based Fluorescent Theranostics for Real-Time Image-Guided Assessment of DNA Damage and Repair

Chemotherapeutic dosing, is largely based on the tolerance levels of toxicity today. Molecular imaging strategies can be leveraged to quantify DNA cytotoxicity and thereby serve as a theranostic tool to improve the efficacy of treatments. Methoxyamine-modified cyanine-7 (Cy7MX) is a molecular probe...

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Detalles Bibliográficos
Autores principales: Srinivasan, Shriya S., Seenivasan, Rajesh, Condie, Allison, Gerson, Stanton L., Wang, Yanming, Burda, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387448/
https://www.ncbi.nlm.nih.gov/pubmed/30678294
http://dx.doi.org/10.3390/ijms20030471