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Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging

Food packaging is not only a simple protective barrier, but a real “active” component, which is expected to preserve food quality, safety and shelf-life. Therefore, the materials used for packaging production should show peculiar features and properties. Specifically, antimicrobial packaging has rec...

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Autores principales: Agrillo, Bruna, Balestrieri, Marco, Gogliettino, Marta, Palmieri, Gianna, Moretta, Rosalba, Proroga, Yolande T.R., Rea, Ilaria, Cornacchia, Alessandra, Capuano, Federico, Smaldone, Giorgio, De Stefano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387462/
https://www.ncbi.nlm.nih.gov/pubmed/30704080
http://dx.doi.org/10.3390/ijms20030601
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author Agrillo, Bruna
Balestrieri, Marco
Gogliettino, Marta
Palmieri, Gianna
Moretta, Rosalba
Proroga, Yolande T.R.
Rea, Ilaria
Cornacchia, Alessandra
Capuano, Federico
Smaldone, Giorgio
De Stefano, Luca
author_facet Agrillo, Bruna
Balestrieri, Marco
Gogliettino, Marta
Palmieri, Gianna
Moretta, Rosalba
Proroga, Yolande T.R.
Rea, Ilaria
Cornacchia, Alessandra
Capuano, Federico
Smaldone, Giorgio
De Stefano, Luca
author_sort Agrillo, Bruna
collection PubMed
description Food packaging is not only a simple protective barrier, but a real “active” component, which is expected to preserve food quality, safety and shelf-life. Therefore, the materials used for packaging production should show peculiar features and properties. Specifically, antimicrobial packaging has recently gained great attention with respect to both social and economic impacts. In this paper, the results obtained by using a polymer material functionalized by a small synthetic peptide as “active” packaging are reported. The surface of Polyethylene Terephthalate (PET), one of the most commonly used plastic materials in food packaging, was plasma-activated and covalently bio-conjugated to a bactenecin-derivative peptide named 1018K6, previously characterized in terms of antimicrobial and antibiofilm activities. The immobilization of the peptide occurred at a high yield and no release was observed under different environmental conditions. Moreover, preliminary data clearly demonstrated that the “active” packaging was able to significantly reduce the total bacterial count together with yeast and mold spoilage in food-dairy products. Finally, the functionalized-PET polymer showed stronger efficiency in inhibiting biofilm growth, using a Listeria monocytogenes strain isolated from food products. The use of these “active” materials would greatly decrease the risk of pathogen development and increase the shelf-life in the food industry, showing a real potential against a panel of microorganisms upon exposure to fresh and stored products, high chemical stability and re-use possibility.
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spelling pubmed-63874622019-02-27 Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging Agrillo, Bruna Balestrieri, Marco Gogliettino, Marta Palmieri, Gianna Moretta, Rosalba Proroga, Yolande T.R. Rea, Ilaria Cornacchia, Alessandra Capuano, Federico Smaldone, Giorgio De Stefano, Luca Int J Mol Sci Article Food packaging is not only a simple protective barrier, but a real “active” component, which is expected to preserve food quality, safety and shelf-life. Therefore, the materials used for packaging production should show peculiar features and properties. Specifically, antimicrobial packaging has recently gained great attention with respect to both social and economic impacts. In this paper, the results obtained by using a polymer material functionalized by a small synthetic peptide as “active” packaging are reported. The surface of Polyethylene Terephthalate (PET), one of the most commonly used plastic materials in food packaging, was plasma-activated and covalently bio-conjugated to a bactenecin-derivative peptide named 1018K6, previously characterized in terms of antimicrobial and antibiofilm activities. The immobilization of the peptide occurred at a high yield and no release was observed under different environmental conditions. Moreover, preliminary data clearly demonstrated that the “active” packaging was able to significantly reduce the total bacterial count together with yeast and mold spoilage in food-dairy products. Finally, the functionalized-PET polymer showed stronger efficiency in inhibiting biofilm growth, using a Listeria monocytogenes strain isolated from food products. The use of these “active” materials would greatly decrease the risk of pathogen development and increase the shelf-life in the food industry, showing a real potential against a panel of microorganisms upon exposure to fresh and stored products, high chemical stability and re-use possibility. MDPI 2019-01-30 /pmc/articles/PMC6387462/ /pubmed/30704080 http://dx.doi.org/10.3390/ijms20030601 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Agrillo, Bruna
Balestrieri, Marco
Gogliettino, Marta
Palmieri, Gianna
Moretta, Rosalba
Proroga, Yolande T.R.
Rea, Ilaria
Cornacchia, Alessandra
Capuano, Federico
Smaldone, Giorgio
De Stefano, Luca
Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging
title Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging
title_full Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging
title_fullStr Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging
title_full_unstemmed Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging
title_short Functionalized Polymeric Materials with Bio-Derived Antimicrobial Peptides for “Active” Packaging
title_sort functionalized polymeric materials with bio-derived antimicrobial peptides for “active” packaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387462/
https://www.ncbi.nlm.nih.gov/pubmed/30704080
http://dx.doi.org/10.3390/ijms20030601
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