Localized Delivery of Pilocarpine to Hypofunctional Salivary Glands through Electrospun Nanofiber Mats: An Ex Vivo and In Vivo Study

Dry mouth or xerostomia is a frequent medical condition among the polymedicated elderly population. Systemic pilocarpine is included in the first line of pharmacological therapies for xerostomia. However, the efficacy of existing pilocarpine formulations is limited due to its adverse side effects an...

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Detalles Bibliográficos
Autores principales: Muthumariappan, Sujatha, Ng, Wei Cheng, Adine, Christabella, Ng, Kiaw Kiaw, Davoodi, Pooya, Wang, Chi-Hwa, Ferreira, Joao N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387464/
https://www.ncbi.nlm.nih.gov/pubmed/30696017
http://dx.doi.org/10.3390/ijms20030541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387464/
https://www.ncbi.nlm.nih.gov/pubmed/30696017
http://dx.doi.org/10.3390/ijms20030541

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