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Localized Delivery of Pilocarpine to Hypofunctional Salivary Glands through Electrospun Nanofiber Mats: An Ex Vivo and In Vivo Study
Dry mouth or xerostomia is a frequent medical condition among the polymedicated elderly population. Systemic pilocarpine is included in the first line of pharmacological therapies for xerostomia. However, the efficacy of existing pilocarpine formulations is limited due to its adverse side effects an...
Autores principales: | Muthumariappan, Sujatha, Ng, Wei Cheng, Adine, Christabella, Ng, Kiaw Kiaw, Davoodi, Pooya, Wang, Chi-Hwa, Ferreira, Joao N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387464/ https://www.ncbi.nlm.nih.gov/pubmed/30696017 http://dx.doi.org/10.3390/ijms20030541 |
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