MUC16 impacts tumor proliferation and migration through cytoplasmic translocation of P120-catenin in epithelial ovarian cancer cells: an original research

BACKGROUND: Epithelial ovarian cancer (EOC) remains one of the most lethal gynecologic cancers, and its pathogenetic mechanism remains unclear. Here we show that MUC16 promotes the translocation of p120-catenin (p120ctn) to the cytoplasm and consequently activates ras homolog (Rho) GTPases RhoA/Cdc4...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Li, Xiaoduan, Wang, Xinjing, Zhu, Qinyi, Wu, Xiaoli, Wang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387523/
https://www.ncbi.nlm.nih.gov/pubmed/30795761
http://dx.doi.org/10.1186/s12885-019-5371-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387523/
https://www.ncbi.nlm.nih.gov/pubmed/30795761
http://dx.doi.org/10.1186/s12885-019-5371-4

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