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Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis

BACKGROUND: Acute chorioamnionitis (aCA), inflammation of the placenta and fetal membranes, is a frequently reported lesion in preterm deliveries. Genetic variants in innate immune system genes such as Interleukin-6 (IL6) may contribute to the placenta’s inflammatory response, thus predisposing some...

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Detalles Bibliográficos
Autores principales: Konwar, Chaini, Del Gobbo, Giulia F., Terry, Jefferson, Robinson, Wendy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387541/
https://www.ncbi.nlm.nih.gov/pubmed/30795743
http://dx.doi.org/10.1186/s12881-019-0768-0