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Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis
BACKGROUND: Acute chorioamnionitis (aCA), inflammation of the placenta and fetal membranes, is a frequently reported lesion in preterm deliveries. Genetic variants in innate immune system genes such as Interleukin-6 (IL6) may contribute to the placenta’s inflammatory response, thus predisposing some...
Autores principales: | Konwar, Chaini, Del Gobbo, Giulia F., Terry, Jefferson, Robinson, Wendy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387541/ https://www.ncbi.nlm.nih.gov/pubmed/30795743 http://dx.doi.org/10.1186/s12881-019-0768-0 |
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