miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects

BACKGROUND: Functional reconstruction of maxillofacial bone defects is a considerable clinical challenge. Many studies have emphasized the osteogenic and angiopoietic abilities of stem cells for tissue regeneration. We previously showed that microRNA-21 (miRNA-21) can promote angiogenesis in human u...

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Detalles Bibliográficos
Autores principales: Yang, Chi, Liu, Xiaohan, Zhao, Kai, Zhu, Youming, Hu, Bin, Zhou, Yong, Wang, Mohan, Wu, Yiqun, Zhang, Chengfei, Xu, Jianguang, Ning, Yujie, Zou, Duohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387542/
https://www.ncbi.nlm.nih.gov/pubmed/30795815
http://dx.doi.org/10.1186/s13287-019-1168-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387542/
https://www.ncbi.nlm.nih.gov/pubmed/30795815
http://dx.doi.org/10.1186/s13287-019-1168-2

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