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Aberrant fatty acid profile and FFAR4 signaling confer endocrine resistance in breast cancer

BACKGROUND: Evidence suggests that fatty acid receptor FFAR4 plays a tumor-promoting role in adipose tissue-adjacent malignancies, but its clinical relevance remains unexplored. Here, we investigated the clinical significance and underlying mechanisms of FFAR4 in hormone receptor-positive breast can...

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Detalles Bibliográficos
Autores principales: Chu, Xiao, Zhou, Qi, Xu, Yingchun, Jiang, Jingting, Li, Qing, Zhou, Qianjun, Wu, Qiong, Jin, Min, Wang, Hui, Gu, Yuting, Wang, Xue, Wang, Bei, He, Songbing, He, Xiaozhou, Wu, Changping, Zhang, Fengchun, Zhang, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387561/
https://www.ncbi.nlm.nih.gov/pubmed/30795784
http://dx.doi.org/10.1186/s13046-019-1040-3