Cargando…

Amine derivatives of furocoumarin induce melanogenesis by activating Akt/GSK-3β/β-catenin signal pathway

BACKGROUND: Melanogenesis, or the biosynthesis of melanin, plays a critical role in the pigmentation of skin, hair, and eyes. Reduced melanogenesis may lead to depigmentation conditions such as vitiligo. Psoralen, a furocoumarin derivative, is closely associated with melanogenesis, and its derivativ...

Descripción completa

Detalles Bibliográficos
Autores principales: Zang, Deng, Niu, Chao, Aisa, Haji Akber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387609/
https://www.ncbi.nlm.nih.gov/pubmed/30858693
http://dx.doi.org/10.2147/DDDT.S180960