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Dexmedetomidine attenuates the neurotoxicity of propofol toward primary hippocampal neurons in vitro via Erk1/2/CREB/BDNF signaling pathways

BACKGROUND: Propofol is a commonly used general anesthetic for the induction and maintenance of anesthesia and critical care sedation in children, which may add risk to poor neurodevelopmental outcome. We aimed to evaluate the effect of propofol toward primary hippocampal neurons in vitro and the po...

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Detalles Bibliográficos
Autores principales: Tu, Youbing, Liang, Yubing, Xiao, Yong, Lv, Jing, Guan, Ruicong, Xiao, Fei, Xie, Yubo, Xiao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387615/
https://www.ncbi.nlm.nih.gov/pubmed/30858699
http://dx.doi.org/10.2147/DDDT.S188436