Cargando…

Alphalipoic Acid Prevents Oxidative Stress and Peripheral Neuropathy in Nab-Paclitaxel-Treated Rats through the Nrf2 Signalling Pathway

Peripheral neuropathy is the major dose-limiting side effect of paclitaxel (PTX), affecting both the quality of life and the survival of cancer patients. Nab-paclitaxel (nab-PTX) was developed to provide additional clinical benefits and overcome the safety drawbacks of solvent-based PTX. However, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Hong, Guo, Xi, Wang, Ziteng, Wang, Peipei, Zhang, Zhe, Dong, Jihong, Zhuang, Rongyuan, Zhou, Yuhong, Ma, Guo, Cai, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387730/
https://www.ncbi.nlm.nih.gov/pubmed/30881589
http://dx.doi.org/10.1155/2019/3142732