Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

BACKGROUND: Administration of anandamide (AEA) or 2-arachidonoylglycerol (2AG) induces CB1 coupling and activation of TRKB receptors, regulating the neuronal migration and maturation in the developing cortex. However, at higher concentrations AEA also engages vanilloid receptor TRPV1, usually with o...

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Detalles Bibliográficos
Autores principales: Diniz, Cassiano R.A.F., Biojone, Caroline, Joca, Samia R.L., Rantamäki, Tomi, Castrén, Eero, Guimarães, Francisco S., Casarotto, Plinio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Animal Behavior
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387754/
https://www.ncbi.nlm.nih.gov/pubmed/30809460
http://dx.doi.org/10.7717/peerj.6493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387754/
https://www.ncbi.nlm.nih.gov/pubmed/30809460
http://dx.doi.org/10.7717/peerj.6493

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