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Elevated Soluble PD-L1 in Pregnant Women's Serum Suppresses the Immune Reaction

Background: Programmed death-ligand 1 (PD-L1) is expressed not only on some cancer cells, but also on the outer surface of placental syncytiotrophoblasts, which is assumed to induce maternal immune tolerance to fetal tissue via programmed death-1 (PD-1) receptors on T cells. Recently, levels of solu...

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Detalles Bibliográficos
Autores principales: Okuyama, Mai, Mezawa, Hidetoshi, Kawai, Toshinao, Urashima, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387906/
https://www.ncbi.nlm.nih.gov/pubmed/30833943
http://dx.doi.org/10.3389/fimmu.2019.00086