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Distinct Contribution of the HtrA Protease and PDZ Domains to Its Function in Stress Resilience and Virulence of Bacillus anthracis

Anthrax is a lethal disease caused by the Gram-positive spore-producing bacterium Bacillus anthracis. We previously demonstrated that disruption of htrA gene, encoding the chaperone/protease HtrA(BA) (High Temperature Requirement A of B. anthracis) results in significant virulence attenuation, despi...

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Detalles Bibliográficos
Autores principales: Israeli, Ma’ayan, Elia, Uri, Rotem, Shahar, Cohen, Hila, Tidhar, Avital, Bercovich-Kinori, Adi, Cohen, Ofer, Chitlaru, Theodor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387919/
https://www.ncbi.nlm.nih.gov/pubmed/30833938
http://dx.doi.org/10.3389/fmicb.2019.00255