Fast, Efficient, and Versatile Synthesis of 6-amino-5-carboxamidouracils as Precursors for 8-Substituted Xanthines

Substituted xanthine derivatives are important bioactive molecules. Herein we report on a new, practical synthesis of 6-amino-5-carboxamidouracils, the main building blocks for the preparation of 8-substituted xanthines, by condensation of 5,6-diaminouracil derivatives and various carboxylic acids u...

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Detalles Bibliográficos
Autores principales: Marx, Daniel, Wingen, Lukas M., Schnakenburg, Gregor, Müller, Christa E., Scholz, Matthias S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387921/
https://www.ncbi.nlm.nih.gov/pubmed/30834241
http://dx.doi.org/10.3389/fchem.2019.00056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387921/
https://www.ncbi.nlm.nih.gov/pubmed/30834241
http://dx.doi.org/10.3389/fchem.2019.00056

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