Glabridin Prevents Doxorubicin-Induced Cardiotoxicity Through Gut Microbiota Modulation and Colonic Macrophage Polarization in Mice

The chemotherapeutic drug doxorubicin (DOX) provokes a dose-related cardiotoxicity. Thus, there is an urgent need to identify the underlying mechanisms and develop strategies to overcome them. Here we demonstrated that glabridin (GLA), an isoflavone from licorice root, prevents DOX-induced cardiotox...

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Detalles Bibliográficos
Autores principales: Huang, Keqing, Liu, Yanzhuo, Tang, Honglin, Qiu, Miao, Li, Chenhong, Duan, Chenfan, Wang, Chenlong, Yang, Jing, Zhou, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387923/
https://www.ncbi.nlm.nih.gov/pubmed/30833897
http://dx.doi.org/10.3389/fphar.2019.00107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387923/
https://www.ncbi.nlm.nih.gov/pubmed/30833897
http://dx.doi.org/10.3389/fphar.2019.00107

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