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Identification of the Germline Mutation Profile in Esophageal Squamous Cell Carcinoma by Whole Exome Sequencing

Background: Esophageal squamous cell carcinoma (ESCC) is associated with poor prognosis and occurs with high frequency in China. The germline mutation profile in ESCC remains unclear, and therefore, the discovery of oncogenic alterations in ESCC is urgently needed. This study investigates the germli...

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Detalles Bibliográficos
Autores principales: Deng, Jiaying, Weng, Xiaoling, Ye, Junyi, Zhou, Daizhan, Liu, Yun, Zhao, Kuaile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387948/
https://www.ncbi.nlm.nih.gov/pubmed/30833958
http://dx.doi.org/10.3389/fgene.2019.00047