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Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression

Antigen presentation on HLA molecules is a major mechanism by which the immune system monitors self and non-self-recognition. Importantly, HLA-I presentation has gained much attention through its role in eliciting anti-tumor immunity. Several determinants controlling the peptides presented on HLA ha...

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Detalles Bibliográficos
Autores principales: Javitt, Aaron, Barnea, Eilon, Kramer, Matthias P., Wolf-Levy, Hila, Levin, Yishai, Admon, Arie, Merbl, Yifat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387973/
https://www.ncbi.nlm.nih.gov/pubmed/30833945
http://dx.doi.org/10.3389/fimmu.2019.00141