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Iterative Variable Gene Discovery from Whole Genome Sequencing with a Bootstrapped Multiresolution Algorithm

In jawed vertebrates, variable (V) genes code for antigen-binding regions of B and T lymphocyte receptors, which generate a specific response to foreign pathogens. Obtaining the detailed repertoire of these genes across the jawed vertebrate kingdom would help to understand their evolution and functi...

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Detalles Bibliográficos
Autores principales: Olivieri, David N., Gambón-Deza, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388353/
https://www.ncbi.nlm.nih.gov/pubmed/30886642
http://dx.doi.org/10.1155/2019/3780245