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Neuronal scaffolding protein spinophilin is integral for cocaine-induced behavioral sensitization and ERK1/2 activation

Spinophilin is a scaffolding protein enriched in dendritic spines with integral roles in the regulation of spine density and morphology, and the modulation of synaptic plasticity. The ability of spinophilin to alter synaptic strength appears to involve its scaffolding of key synaptic proteins, inclu...

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Detalles Bibliográficos
Autores principales: Areal, Lorena Bianchine, Hamilton, Alison, Martins-Silva, Cristina, Pires, Rita Gomes Wanderley, Ferguson, Stephen S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388481/
https://www.ncbi.nlm.nih.gov/pubmed/30803445
http://dx.doi.org/10.1186/s13041-019-0434-7