Simplified in vitro engineering of neuromuscular junctions between rat embryonic motoneurons and immortalized human skeletal muscle cells

BACKGROUND: Neuromuscular junctions (NMJs) consist of the presynaptic cholinergic motoneuron terminals and the corresponding postsynaptic motor endplates on skeletal muscle fibers. At the NMJ the action potential of the neuron leads, via release of acetylcholine, to muscle membrane depolarization th...

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Detalles Bibliográficos
Autores principales: Saini, Jasdeep, Faroni, Alessandro, Abd Al Samid, Marwah, Reid, Adam J, Lightfoot, Adam P, Mamchaoui, Kamel, Mouly, Vincent, Butler-Browne, Gillian, McPhee, Jamie S, Degens, Hans, Al-Shanti, Nasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388735/
https://www.ncbi.nlm.nih.gov/pubmed/30863121
http://dx.doi.org/10.2147/SCCAA.S187655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388735/
https://www.ncbi.nlm.nih.gov/pubmed/30863121
http://dx.doi.org/10.2147/SCCAA.S187655

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