Maresin 1 mitigates renal ischemia/reperfusion injury in mice via inhibition of the TLR4/MAPK/NF-κB pathways and activation of the Nrf2 pathway

BACKGROUND: Inflammation and oxidative stress play a crucial role in the pathogenesis of renal ischemia/reperfusion injury (IRI). Maresin 1 (MaR1), which has shown strong anti-inflammatory and antioxidant effects, was recently reported to have protective properties in several different animal models...

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Detalles Bibliográficos
Autores principales: Qiu, Yun, Wu, Yichen, Zhao, Hongmei, Sun, Hong, Gao, Sumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388965/
https://www.ncbi.nlm.nih.gov/pubmed/30863013
http://dx.doi.org/10.2147/DDDT.S188654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388965/
https://www.ncbi.nlm.nih.gov/pubmed/30863013
http://dx.doi.org/10.2147/DDDT.S188654

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