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The prognostic value of Tiam1 correlates with its roles in epithelial–mesenchymal transition progression and angiogenesis in lung adenocarcinoma

BACKGROUND: Tiam1 has been identified as an oncogene and acts as an activator of GTPase Rac. Tiam1 was reported to be a promoter of cancer progression in various cancer types, while in lung adenocarcinoma, its mechanism of action is poorly understood. MATERIALS AND METHODS: Immunohistochemistry stai...

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Detalles Bibliográficos
Autores principales: Zhu, Guang, Zhang, Yuan, Wang, Qianrong, Che, Shuanlong, Yang, Yang, Chen, Liyan, Lin, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388966/
https://www.ncbi.nlm.nih.gov/pubmed/30863182
http://dx.doi.org/10.2147/CMAR.S195093