Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats

BACKGROUND: Alzheimer disease (AD) is the main cause of dementia in elderly people. The potential of histamine H3 receptor (H3R) antagonists as a pharmacological treatment of several neuropsychiatric diseases is well established. METHODS: The novel non-imidazole-based H3R antagonist E177 was screene...

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Detalles Bibliográficos
Autores principales: Alachkar, Alaa, Khan, Nadia, Łażewska, Dorota, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388968/
https://www.ncbi.nlm.nih.gov/pubmed/30863075
http://dx.doi.org/10.2147/NDT.S193125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388968/
https://www.ncbi.nlm.nih.gov/pubmed/30863075
http://dx.doi.org/10.2147/NDT.S193125

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