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Mismatch repair status and high expression of PD-L1 in nasopharyngeal carcinoma

PURPOSE: To analyze the mismatch repair (MMR) status and PD-L1 expression in nasopharyngeal carcinoma (NPC), and investigate whether PD-L1 and MMR status could be used as a biomarker for predicting response of immune checkpoint blockades (ICBs) treatment. PATIENTS AND METHODS: A total of 108 patient...

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Detalles Bibliográficos
Autores principales: Zhao, Liang, Liao, Xiyi, Hong, Ganji, Zhuang, Yanzhen, Fu, Kaili, Chen, Peiqiong, Wang, Yuhuan, Chen, Haojun, Lin, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388969/
https://www.ncbi.nlm.nih.gov/pubmed/30863173
http://dx.doi.org/10.2147/CMAR.S193878